NAD+NICOTINAMIDE ADENINE DINUCLEOTIDE
Oxidised β-NAD — the central redox coenzyme and substrate for sirtuins and PARPs.
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For laboratory research use only. Not for human or veterinary consumption, diagnostic or therapeutic use. Handle in accordance with institutional safety procedures.
Product Overview
Scientific profile
β-Nicotinamide adenine dinucleotide (NAD⁺) is the oxidised form of a coenzyme found in every living cell. It consists of two nucleotides — one bearing nicotinamide, the other adenine — joined through their phosphate groups.
Research Background
NAD⁺ accepts hydride ions in glycolysis, the TCA cycle and fatty-acid oxidation, being reduced to NADH, which in turn fuels oxidative phosphorylation. Beyond redox chemistry, NAD⁺ is consumed as a substrate by sirtuin deacylases (SIRT1–7), poly(ADP-ribose) polymerases (PARPs) and the NADase CD38. Declining tissue NAD⁺ levels in ageing rodent models have made NAD⁺ metabolism a major focus of longevity research.
Areas of Investigation
- Cellular bioenergetics and mitochondrial respiration assays
- Sirtuin and PARP enzymology
- NAD⁺ salvage-pathway biology (NAMPT, NMN, NR)
- Age-associated changes in NAD⁺ metabolism in preclinical models
Analytical Profile
Not a peptide — purity determined by HPLC (UV 260 nm); identity confirmed by mass spectrometry. Hygroscopic white to off-white solid; aqueous solutions should be prepared fresh.
Specifications
Chemical & physical data
CAS Number
53-84-9
Molecular Formula
C21H27N7O14P2
Molecular Weight
663.43 g/mol
Physical Form
Lyophilized Powder
Storage Guidelines
-20°C, desiccated and protected from light (hygroscopic)
Amino Acid Sequence
Not applicable — dinucleotide (non-peptide)
Nicotinamide riboside 5′-phosphate and adenosine 5′-phosphate joined by a pyrophosphate bridge
Quality Assurance
Every vial. Every batch. Documented.
Our release process is built for research reproducibility — independent analytics, traceable batches and tamper-evident authentication.
>99% Purity Guaranteed
Every batch must exceed 99% purity by reverse-phase HPLC before it is released to the catalog.
3rd Party Laboratory Tested
Independent analytical labs confirm purity by HPLC and molecular identity by mass spectrometry (MS).
Batch-Tracked Serialization
Each box carries a unique 6-character code linked to its production batch and verifiable online.
Strict Research-Grade Synthesis
Solid-phase synthesis, lyophilization and sealed vialing under controlled, documented conditions.
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